Literature summary extracted from

Dobo, J.; Gal, P.; Szilagyi, K.; Cseh, S.; L�rincz, Z.; Schumaker, V.N.; Zavodszky, P.
One active C1r subunit is sufficient for the activity of the complement C1 complex: stabilization of C1r in the zymogen form by point mutations (1999), J. Immunol., 162, 1108-1112.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
3.4.21.41	expression in insect cells	Homo sapiens

Protein Variants

EC Number	Protein Variants	Comment	Organism
3.4.21.41	R463X	the mutants of the proenzyme Arg463Lys,Ile464Phe have increased stability, they retain their ability to autoactivate and have wild-type like hemolytic activity	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.21.41	Homo sapiens	-	-	-

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Release 2023.1 (January 2023)